Medikamentenliste Druckansicht – G6PD-Mangel / Favismus

Name	Risikostufe	unsicher	sicher*	Molekularformel	Notiz	Für wen
2-Naphthol	High			C10¬†H8¬†O		All
Acetanilide (acetanilid)	High			C8¬†H9¬†N O		Medit., Asia
Acetazolamide	Medium			C4¬†H6¬†N4¬†O3¬†S2		All
Acetophenetidin (phenacetin)	Low			-¬†		All
Acetylphenylhydrazine (2-Phynylacetohydrazide)	High			C8¬†H10¬†N2¬†O	These substances taken in high quantities might cause hemolysis also with normal subjects.	All
Aldesulfone sodium (sulfoxone)	High			C14¬†H14¬†N2¬†Na2¬†O6S3		All
Aminophenazone (aminopyrine)	Medium			C13¬†H17¬†N3¬†O		All
Aminopyrine (Pyramidon, amidopyrine)	Low			-¬†		All
Antazoline (antistine)	Medium			C17¬†H19¬†N3		All
Antipyrine	Low			-¬†		All
Arginine (2-Amino-5-guanidinopentanoic acid)	Medium			C6¬†H14¬†N4¬†O2		All
Arsine	High			As-H3	These substances taken in high quantities might cause hemolysis also with normal subjects.	All
Ascorbic Acid	High			C6¬†H8¬†O6		All
Azathioprine (use with caution)	Low			-¬†	Use with caution and not in combination with other drugs.	All
Baclofen (use with caution)	Low			-¬†	Use with caution and not in combination with other drugs.	All
Bean of St.Ignatius (Strychnos ignatii)	Medium			-¬†		All
Benorilate	Medium			C17¬†H15¬†NO5		All
Benzexolo	Low			-¬†		All
Beta-Naphthol (2-Naphthol)	High			C10¬†H8¬†O		All
Brinzolamide	High			-¬†	See https://marineyes.com/glaucoma/medications.html	All
Bupivacaine	High			C18¬†H28¬†N2¬†O		All
Calcium Carboxylate	Medium			-¬†		All
Carbutamide	Medium			C11¬†H17¬†N3¬†O3¬†S		All
Chloramphenicol	High			C11¬†H12¬†C12¬†N2¬†O5		Medit., Asia
Chloroquine	High			C18¬†H26¬†Cl N3	If required, this substance may be taken under medical supervision as a preventive treatment or cure of malaria.	Medit., Asia
Chloroquine + Proguanil	High			-¬†		Medit., Asia
Ciprofloxacin	High			-¬†		All
Clorguanidina	Low			-¬†		All
Colchicine	Medium			C22¬†H25¬†N O6		All
Dapsone (diaphenylsulfone)	High			C12¬†H12¬†N2¬†O2¬†S	These substances taken in high quantities might cause hemolysis also with normal subjects.	All
Diethylamine	High			C4¬†H11¬†N		All
Dimenidrinato	High			C24¬†H28¬†ClN5¬†O3		All
Dimercaprol	High			C3¬†H8¬†O S2		All
Diphenhydramine	Low			-¬†		All
Diphenhydramine (difenilhydramine)	Medium			C17¬†H21¬†N O		All
Dopamine¬†	Medium			C8¬†H11¬†N O2		All
Dorzolamide¬†	High			-¬†	See https://marineyes.com/glaucoma/medications.html	All
Doxorubicin	High			C27¬†H29¬†N O11		Medit., Asia
Enoxacin	High			C15¬†H17¬†F4¬†N4¬†O3		All
Epirubicin	Medium			C27¬†H29¬†NO11		All
Flumequine	Medium			C14¬†H12¬†FNO3		All
Furazolidone	High			C8¬†H7¬†N3¬†O5		All
Glibenclamide	High			C32¬†H28¬†Cl N3¬†O5¬†S	Hemolytic reactions to this substance have been reported only in few, isolated cases and no written reference exists as of this time.	Medit., Asia
Glibornuride	Medium			C18¬†H26¬†N2¬†O4¬†S		All
Gliclazide	High			C15¬†H21¬†N3¬†O3¬†S		All
Glimepiride	High			C24¬†H34¬†N4¬†O5¬†S		All
Glipizide	High			C21¬†H27¬†N5¬†O4¬†S		All
Glucosulfone (glucosulfone sodium)	High			C24¬†H34¬†N2¬†Na2O18¬†S3		All
Hydroxychloroquine	High			C18¬†H26¬†ClN3¬†O		All
Indigofera Tinctoria	Medium			-¬†		All
Isobutyl Nitrite	High			C4¬†H9¬†N O2		Medit., Asia
Isoniazid	Medium			C6¬†H7¬†N3¬†O		All
Lawsone Inermis	Medium			-¬†		All
Levodopa	Medium			C9¬†H11¬†NO4		All
Levofloxacin	High			C18¬†H20¬†FN3¬†O4		Medit., Asia
Lomefloxacin	High			C17¬†H19¬†F2¬†N3¬†O3		All
Mefloquine	High			C17¬†H16¬†F6¬†N2¬†O		All
Menadiol Sodium Sulfate (Vitamin k4 sodium sulfate)	High			C11¬†H8¬†Na2¬†O8¬†S2	Synthetic substitutes of natural Vitamin K. Other substitutes non listed here are: menadiole diacetate, menadiole sodium phosphate (anhydrous salt). As treatment of hemorrhage in newborns, a single dose of this substance may be given (via parenteral) on the first day after birth and is well tolerated. The writers of these note (2,16) generally consider all Vitamin K substitutes as potentially hemolysis inducing substances. It is probable that natural Vitamin K1 (phyto-menadione) presents a lower risk.	All
Menadione (menaphtone)	High			C11¬†H8¬†O2	Synthetic substitutes of natural Vitamin K. Other substitutes non listed here are: menadiole diacetate, menadiole sodium phosphate (anhydrous salt). As treatment of hemorrhage in newborns, a single dose of this substance may be given (via parenteral) on the first day after birth and is well tolerated. The writers of these note (2,16) generally consider all Vitamin K substitutes as potentially hemolysis inducing substances. It is probable that natural Vitamin K1 (phyto-menadione) presents a lower risk.	All
Menadione sodium Bisulfite (Vitamin K3 sodium bisulfite)	High			C11¬†H8¬†O2¬†NaHSO3	Synthetic substitutes of natural Vitamin K. Other substitutes non listed here are: menadiole diacetate, menadiole sodium phosphate (anhydrous salt). As treatment of hemorrhage in newborns, a single dose of this substance may be given (via parenteral) on the first day after birth and is well tolerated. The writers of these note (2,16) generally consider all Vitamin K substitutes as potentially hemolysis inducing substances. It is probable that natural Vitamin K1 (phyto-menadione) presents a lower risk.	All
Mepacrine (Quinacrine)	High			C23¬†H3¬†O Cl N3¬†O		Medit., Asia
Mesalazine - 5-Aminosalicylic Acid (paraminosalicylic acid)	High			C7¬†H7¬†N O3		Medit., Asia
Metamizole	High			C13¬†H16¬†N3¬†NaO4¬†S		Medit., Asia
Methyltioninium Chloride (methylene blue)	High			C16¬†H18¬†Cl N3¬†S		All
Morpholine	Medium			C4¬†H9¬†NO		All
Moxifloxacin	High			-¬†		Medit., Asia
Nalidixic Acid	High			C12¬†H12¬†N2¬†O3	Hemolytic reactions to this substance have been reported only in few, isolated cases and no written reference exists as of this time.	Medit., Asia
Naphtalene, Pure (naphtalin)	High			C10¬†H8		All
Niridazole	High			C6¬†H6¬†N4¬†O3¬†S		All
Nitric Oxide	High			NO		All
Nitrofural (nitrofurazone)	High			C6¬†H6¬†N4¬†O4		All
Nitrofurantoin	High			C8¬†H6¬†N4¬†O5		All
Nitroglycerin¬†	High			C3¬†H5¬†N3¬†O9		All
Noramidopyrine	High			C13¬†H16¬†N3¬†NaO4¬†S		All
Norfloxacin	Medium			C16¬†H18¬†F N3¬†O3		All
O-Acetylsalicylic Acid (acetylsalicylic acid)	High			C9¬†H8¬†O4	Among the alternatives are Paracetamol, which is generally considered safe, and flurbiprophene.	Medit., Asia
O-Acetylsalicylic Acid + Acetanilide	High			-¬†		Medit., Asia
O-Acetylsalicylic Acid + Ascorbic Acid	High			-¬†		All
O-Acetylsalicylic Acid + Paracetamol	High			-¬†	Beware of - genetic G-6-PD deficiency (favism) - After paracetamol administration, hemolytic anemia may occur due to the reduced supply of glutathione	All
Ofloxacin	High			-¬†		Medit., Asia
Oxidase, Urate (urate oxidase)	High			-¬†		Medit., Asia
Pamaquine	High			C42¬†H45¬†N3¬†O7		All
Para-Aminobenzoic Acid (4-Aminobenzoic Acid)	Medium			C7¬†H7¬†N O2		All
Paracetamol (acetaminophen)	Medium			C8¬†H9¬†N O2		All
Paracetamol + Propyphenazone	Medium			-¬†		All
Pefloxacin	High			C17¬†H20¬†N3¬†O3		All
Pentaquine	High			C18¬†H27¬†N3¬†O		All
Phenacetin (acetophenetidin)	High			C10¬†H13¬†N O2	Probably safe in moderate doses.	Medit., Asia
Phenazone (antipyrine)	Medium			C11¬†H12¬†N2¬†O		All
Phenazopyridine	High			C11¬†H11¬†N5		Medit., Asia
Phenylbutazone	Medium			C19¬†H20¬†N2¬†O2		All
Phenytoin	Medium			C19¬†H20¬†N2¬†O2		All
Phynylhydrazine	High			C6¬†H8¬†N2		All
Phytomenadione (Vitamin K1)	Medium			C31¬†H46¬†O2		All
Pipemidic Acid	High			C14¬†H17¬†N5¬†O3		All
Pregabalin (use with caution)	Low			-¬†	Use with caution and not in combination with other drugs.	All
Prilocaine	Medium			C13¬†H20¬†N2¬†O		All
Primaquine	High			C15¬†H21¬†N3¬†O	May be given in reduces doses under medical supervision.	All
Probenecid	High			C13¬†H19¬†NO4¬†S		All
Procainamide	Medium			C13¬†H21¬†N3¬†O		All
Procainamide Hydrochloride	Low			-¬†		All
Proguanil (chlorguanidine)	Medium			C11¬†H16¬†Cl N5		All
Propylene Glycol	Medium			C3¬†H8¬†O2		All
Propyphenazone¬†	Medium			-¬†		All
Pyrimethamine	Medium			C12¬†H13¬†Cl N4		All
Quinidine	Medium			C20¬†H24¬†N2¬†O2		All
Quinidine + Phynylhydrazine	High			-¬†		All
Quinidine + Quinine	Medium			-¬†		All
Quinine	Medium			C20¬†H24¬†N2¬†O2		All
Rasburicase	High			-¬†	Helps clear uric acid from the blood.	Medit., Asia
Sodium nitroprusside¬†	High			Na2¬†[Fe(CN)5¬†NO]		All
Spiramycin	High			C43¬†H74¬†N2¬†O14		All
Stibophen (2-(2-Oxido-3,5-Disulphonatophenoxy)-1,3,2,Benzodioxastibole-4-6-Disulphonate)	High			C12¬†H4¬†Na5¬†O16¬†S4Sb		All
Streptomycin	Medium			C21¬†H39¬†N7¬†O12		All
Succimer	Medium			C4¬†H6¬†O4¬†S2		All
Sulfacetamide	High			C8¬†H10¬†N2¬†O3¬†S		All
Sulfacytine	Medium			C12¬†H14¬†N4¬†O3¬†S		All
Sulfadiazine	Medium			C10¬†H10¬†N4¬†O2¬†S		All
Sulfadiazine	Medium			-¬†		Medit., Asia
Sulfadiazine + Trimethoprim	Medium			-¬†		All
Sulfadimidine	High			C12¬†H14¬†N4¬†O2¬†S		All
Sulfadoxine	Medium			C12¬†H14¬†N4¬†O4¬†S		All
Sulfafurazole (sulfafurazone, sulfisoxazole)	High			C11¬†H13¬†N3¬†O3¬†S		Medit., Asia
Sulfaguanidine	Medium			C7¬†H10¬†N4¬†O2¬†S		All
Sulfamerazine	Medium			C11¬†H12¬†N4¬†O2¬†S		All
Sulfamethizole	Medium			C9¬†H10¬†N4¬†O2¬†S2		All
Sulfamethoxazole	High			C10¬†H11¬†N3¬†O3¬†S	A component, together with Trimetroprim, of Co-trimoxazole.	All
Sulfamethoxypyridazine	Medium			C11¬†H12¬†N4¬†O3¬†S		All
Sulfanilamide (Sulphanilamide)	High			C6¬†H8¬†N2¬†O2¬†S		All
Sulfapyridine	High			C11¬†H11¬†N3¬†O2¬†S		All
Sulfasalazine, Salazosulfapyridine (salazopyrin)	High			C18¬†H14¬†N4¬†O5¬†S	For treating Ulcerative Colitis, Crohn's Disease, Rheumatoid Arthritis, Fibromyalgia.	All
Sulfisoxazole (Gantrisin)	Low			-¬†		All
Sulfoxone	Medium			C14¬†H16¬†N2¬†O6¬†S3		All
Thiamphenicol	High			C12¬†H15¬†Cl2¬†NO5¬†S		All
Thiazosulfone (thiazolesulfone)	High			C9¬†H9¬†N3¬†O2¬†S2		Medit., Asia
Tiaprofenic Acid	Medium			C14¬†H12¬†O3¬†S		All
Tolonium Chloride, Tolonium Chloride (toluidine blue)	High			C15¬†H16¬†Cl N3¬†S		All
Trihexyphynidyl (benzhexol)	Medium			C20¬†H31¬†N O		All
Trimethoprim	Medium			C14¬†H18¬†N4¬†O3	Component, together with Sulfametossazole, of Co-trimoxazolo.	All
Trimethoprim + Sulfamethoxazole¬†	High			-¬†		All
Trinitrotoluene (2,4,6-Trinitrotoluene)	High			C7¬†H5¬†N3¬†O6		Medit., Asia
Tripelennamine	Medium			C16¬†H21¬†N3		Medit., Asia
Alfentanil	eingeschränkt sicher - siehe weiter rechts		[33]
Ascorbinsäure	eingeschränkt sicher - siehe weiter rechts		[6, 10, 17, 18, 46]
ASS (low dose)	eingeschränkt sicher - siehe weiter rechts		[3, 6, 10, 17, 18, 39, 46]
Chloramphenicol	eingeschränkt sicher - siehe weiter rechts		[6, 10, 17, 18, 39, 46]
Fentanyl	eingeschränkt sicher - siehe weiter rechts		[2, 12,15, 17, 24, 26, 33, 37, 44]
Glibenclamid	eingeschränkt sicher - siehe weiter rechts		[46]
Isofluran	eingeschränkt sicher - siehe weiter rechts		[12, 15, 26, 40, 44]
Isoniazid	eingeschränkt sicher - siehe weiter rechts		[6, 17, 18, 46]
Metamizol	eingeschränkt sicher - siehe weiter rechts		[46]
Midazolam	eingeschränkt sicher - siehe weiter rechts		[2,12, 17, 26, 44]
Nitroprussid	eingeschränkt sicher - siehe weiter rechts		[34]
Paracetamol	eingeschränkt sicher - siehe weiter rechts		[10.19, 31, 44, 46]
Penicillin	eingeschränkt sicher - siehe weiter rechts		[24]
Prilocain	eingeschränkt sicher - siehe weiter rechts		[17, 18, 46]
Remifentanil	eingeschränkt sicher - siehe weiter rechts		[33]
Sevofluran	eingeschränkt sicher - siehe weiter rechts		[26,37,44]
Streptomycin	eingeschränkt sicher - siehe weiter rechts		[6, 17, 18, 46]
Trimethoprim	eingeschränkt sicher - siehe weiter rechts		[6, 17, 18, 46]
Vitamin K	eingeschränkt sicher - siehe weiter rechts		[6, 10, 18, 46]
Alfentanil	High	[17]
Ascorbinsäure	High	[10, 15, 46]
ASS (low dose)	High	[10, 11, 15, 35, 46]
Chloramphenicol	High	[3, 10, 11, 15, 46]
Fentanyl	High	[33]
Glibenclamid	High	[6, 46]
Isofluran	High	[4,17]
Isoniazid	High	[15, 46]
Metamizol	High	[6,15, 46]
Midazolam	High	[4]
Nitroprussid	High	[40]
Paracetamol	High	[17, 20, 27, 28, 36, 44, 46]
Penicillin	High	[15]
Prilocain	High	[15]
Remifentanil	High	[33]
Sevofluran	High	[4,17]
Streptomycin	High	[15]
Trimethoprim	High	[10, 42, 46]
Vitamin K	High	[10, 15, 17]
Amikacin	sicher		[6,18,31]
Bupivacain	sicher		[44]
Chloroquin	sicher		[2, 26]
Glycopyrrolat	sicher		[44]
Halothan	sicher		[4, 17]
Heparin	sicher		[12, 34]
Ibuprofen	sicher		[31]
Ketamin	sicher		[4, 17]
Mannitol	sicher		[12, 44]
N2O	sicher		[37, 40, 44]
Neostigmin	sicher		[44]
Paracetamol	sicher		[6, 18, 31]
Parecoxib	sicher		[31]
Pethidin	sicher		[33]
Phenytoin	sicher		[6, 17, 18, 46]
Propofol	sicher		[2, 17, 37]
Rocuronium	sicher		[44]
Succinylcholin	sicher		[15]
Sufentanil	sicher		[31]
Thiopental	sicher		[15, 40]
Tramadol	sicher		[31]
Acetanilid	High	[6]
Acetazolamid	High	[15]
ASS (high dose)	High	[46]
Co-Trimoxazol	High	[10, 42, 46]
Dapson	High	[10, 15,17, 18, 46]
Diclofenac	High	[15]
Diazepam	High	[4, 15, 17]
Gentamicin	High	[24]
Lidocain	High	[15,17]
Methylenblau	High	[6,7, 15, 17, 18, 46]
Metoclopramid	High	[15]
Naphtalin	High	[6]
Nitrofurantoin	High	[6, 10, 15, 17, 18, 46]
Penicillin	High	[15]
Phenazopyridin	High	[6, 10, 46]
Prilocain (EMLA-Creme)	High	[6, 16]
Primaquin	High	[3,6,10,15,17,18,46]
Chinolon-Antibiotika, z. B. Ciprofloxacin	High	[6, 10, 15, 46]
Rasburicase	High	[8, 32, 46]
Sulfonamid-Antibiotika	High	[3, 6, 10, 15, 17, 18]
Toluidinblau	High	[6, 15, 17, 18, 46]

* = in normalen therapeutischen Dosen und / oder bei milden G-6-PD-Varianten